Isotonix® Coenzyme Q10 Special

• Helps maintain a strong heart muscle
• Helps maintain normal blood pressure
• Helps increase energy

Gluten-Free - The finished product contains no detectable gluten

No Detectable GMO - The finished product contains no detectable genetically modified organisms.

Vegan - The product is made without ingredients produced by or derived from animals.

Isotonic-Capable Supplements - Easy-to-swallow isotonic supplements that allow for better nutrient absorption by the body.

No Pork - This product contains no pork or pork products.

Quality Standards - GMP Operations and Standardized Ingredients

Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Potency, Purity and Identity

Coenzyme Q10
Coenzyme Q10 belongs to a family of substances called ubiquinones, and is a water-insoluble, wax-like substance, that is part of the respiratory chain. It is synthesized in the cells, and is involved in electron transport and energy production in mitochondria. In the cellular system, it functions to generate energy from oxygen, in the form of ATP, for bodily processes. CoQ10 also exhibits activity as a free radical scavenger and an antioxidant. The antioxidant activity in the mitochondria and cell membranes protects against peroxidation of lipid membranes.

Coenzyme Q10 can be found in spinach, broccoli, nuts, meats and fish. In the body, it is found in the highest concentration in the cells of the heart, liver, kidney and pancreas. Supplementation of CoQ10 might be beneficial mostly to adults, because the levels of it in the body tend to peak around the age of twenty, and then decline with age. The affects of supplementation with CoQ10 have shown to be especially helpful in maintaining heart health.

Vitamin E
Since vitamin E is one of the most powerful fat-soluble antioxidants in the body, it helps protect cell membranes from the damage caused by free radicals. High doses of vitamin E have been found to support a healthy heart. Vegetable oils, margarine, nuts, seeds, avocados, wheat germ, and safflower oil are all good food sources of vitamin E.

Lipase
Lipase is a fat-digesting enzyme that is used by the body to break down dietary fats into an absorbable form. It is a water-soluble enzyme that catalyzes the hydrolysis of ester bonds in water-insoluble, lipid substrates. Lipase, such as human pancreatic lipase, act to convert triglyceride substrates found in oils from food to monoglycerides and free fatty acids. Lipases are ubiquitous in living organisms. Some lipases also work within the interior spaces of living cells to degrade lipids.

Vitamin B2
Vitamin B2, also known as riboflavin, is a water soluble vitamin that’s primary function as a coenzyme for metabolic processes in the body. A key function of the vitamin is in the production of energy, where it acts as part of the electron transport chain that produces cellular energy.

Requirements for vitamin B2 are associated with calorie intake, because with an increase food intake your body also needs an increase of vitamin B2 to carry out the metabolic processes that will convert the food into usable energy. Nutritional inaccuracy is a common cause of vitamin B2 deficiency, which can occur in the elderly. Foods that are rich in the vitamin B2 are organ meats, eggs, milk, cheese, yogurt, leafy green vegetables, and whole grains.

Potassium
Potassium, in the body, is classified as an electrolyte and is involved in electrical and cellular functions in the body. It aids in regulating water balance, levels of acidity, maintenance of blood pressure, muscle contraction and heartbeat.

Potassium can be found in foods, which help to maintain the body’s internal balance of fluids and chemicals. Some potassium-enriched foods are fruits, vegetables and legumes, which are all commonly recommended for optimal heart health.

What is Coenzyme Q10?
Coenzyme Q10 is actually a two-part compound that is composed of (1) a long, fat-soluble isoprenoid tail that anchors the molecule in the inner membrane of the mitochondria and (2) a quinone that is capable of accepting and transferring electrons through a portion of the respiratory chain. A coenzyme is a non-protein substance that helps enzymes carry out their metabolic function and is not consumed in the reaction. The "Q" stands for quinone and the "10" stands for the number of isoprenoid units in the tail portion of the molecule. Mammals generally have 10 isoprenoid units in the tail portion, but other non-mammalian species may have fewer units. Coenzyme Q10 is a critical biochemical link in the production of energy in the cell. Coenzyme Q10 is found in the cell membranes of all cells in our body, particularly in the inner mitochondrial membranes, and it is especially concentrated in highly active organs such as the heart, lungs, kidneys, spleen, and adrenal glands. The mitochondria produce large amounts of adenosine triphosphate (ATP), which helps cells perform work.

Since the manufacture of adenosine triphosphate (ATP) in the mitochondria is known to generate many harmful oxygen radicals, coenzyme Q10 serves an antioxidant function in that location by neutralizing radicals. Coenzyme Q10 is also required by a key enzyme in the Kreb's cycle (Citric Acid Cycle), which converts both carbohydrates and fat into usable energy for the cell.

What is the source of Coenzyme Q10?
While our livers produce small amounts of coenzyme Q10 and this small amount is distributed to the rest of the body, we get most of this compound from foods such as organ meats, muscle meats, fish, peanuts, spinach, soy, and nuts. In the past it was difficult and very expensive to isolate sufficient amounts of coenzyme Q10 from these food sources for the purpose of dietary supplementation. However, a Japanese company succeeded in synthesizing coenzyme Q10 in 1977, thus making an important nutrient available to the world.

While there is substantial debate about the nature and definition of coenzyme Q10 deficiency and its manifestations, it is well documented that individuals with congestive heart failure, cardiomyopathy, angina pectoris, and chronic gum disease or those who are obese have significantly lower tissue concentrations of coenzyme Q10. Other people at risk for coenzyme Q10 deficiency include cancer patients receiving the anti-cancer drug Adriamycin which can damage the heart and people taking cholesterol-lowering drugs of the HMG-coenzyme A reductase class. It has also been demonstrated that coenzyme Q10 concentrations in various tissues begin to decline as we age.

What is a safe and effective dose of supplemental Coenzyme Q10?
Daily doses as low as 30 mg and as high as 150 mg of coenzyme Q10 are safe and can promote a healthier life. The circulating levels of coenzyme Q10 take about 60-90 days to reach steady state, depending on the dose taken. Granular coenzyme Q10, as used in Isotonix, is about equal to the oil-based form in terms of uptake from the small intestine and distribution throughout the body.

Are there any warnings associated with taking Isotonix Coenzyme Q10?
Do not take while on warfarin [Coumadin] therapy without medical advice. If you are currently using prescription medications, have an ongoing medical condition, or if you are pregnant or breastfeeding, you should consult your healthcare provider before using this product.

Does Isotonix Coenzyme Q10 contain pork or pork products?
No.

Does this product have “No Detectable GMOs”?
This product is tested with no GMO detected. This product’s raw material may contain genetically modified materials/ingredients, but the finished product does not contain any transgenic DNA fragments or transgenic proteins.

Is Isotonix Coenzyme Q10 manufactured in a Good Manufacturing Practice (GMP) facility?
Yes, this product is manufactured in a GMP compliant facility which is inspected by the Food and Drug Administration (FDA) of the United States of America.